Creates the Safety and Opportunity for Girls Act. Provides that notwithstanding any other law to the contrary, no receipt of State funding may be contingent upon an educational institution forgoing the maintenance of sex-segregated spaces by the educational institution, including bathrooms and locker rooms. Provides that notwithstanding any other law to the contrary, no receipt of State funding may be contingent upon an educational institution forgoing the maintenance of sex-segregated athletic or academic programs by the educational institution.

Amends the Interscholastic Athletic Organization Act. Provides that any athletic team or sport that is under the jurisdiction of an association or entity that provides for interscholastic athletics or athletic competition among schools and student must be expressly designated as (i) a male athletic team or sport, (ii) a female athletic team or sport, or (iii) a coeducational athletic team or sport. Provides that an athletic team or sport designated as being female is available only to participants who are female, based on their biological sex. Requires a school district or nonpublic school to obtain a written statement signed by a student's parent or guardian or the student verifying the student's age, biological sex, and that the student has not taken performance enhancing drugs; provides for a penalty for false or misleading statements. Prohibits a governmental entity or an association or entity that provides for interscholastic athletics or athletic competition among schools and students from entertaining a complaint, opening an investigation, or taking any other adverse action against a school district or nonpublic school for maintaining athletic teams or sports in accordance with these provisions.

Creates the Freedom of Education Act. Makes findings. Provides that no public school district or public institution of higher education shall direct, require, or otherwise compel a student to personally affirm, adopt, or adhere to specified tenets. Provides that, notwithstanding any other provision of law or administrative rule to the contrary, a school board, parent, legal guardian, or student has the right to object to and refuse any unit of instruction or required course of study that directs, requires, or otherwise compels a student to personally affirm, adopt, or adhere to any of the specified tenets. Provides that school boards have to review and resolve objections to the school curriculum. Provides a list of ways to remedy objections. Provides that a school board may submit a certified question to the applicable board of elections to approve or disapprove of funding the curriculum. Provides that, notwithstanding any provision of law to the contrary, no distinction or classification of students may be made on account of race or color; however, nothing in this provision may be construed to prohibit the required collection or reporting of demographic data by public school districts or public institutions of higher education. Makes other changes. Effective immediately.

Amends the Medical Practice Act of 1987. Provides that sex-reassignment procedures are prohibited for patients younger than 18 years of age. Provides that if sex-reassignment procedures are administered or performed on patients 18 years of age or older, consent must be provided as specified. Provides that the Department of Financial and Professional Regulation shall revoke the license of any physician who willfully or actively violates the prohibition on sex-reassignment procedures for patients younger than 18 years of age. Amends the Hospital Licensing Act and the Ambulatory Surgical Treatment Center Act. Adds a failure to comply with the provisions as grounds for fines, license denial, license suspension or revocation, or refusal to renew a hospital or facility's license. Amends the Illinois Administrative Procedure Act to provide for emergency rulemaking.

Amends the Department of Public Health Powers and Duties Law of the Civil Administrative Code. Provides that a health care professional shall report to the Department of Public Health each time the health care professional prescribes a puberty blocker to a person under the age of 18. Provides that the report shall be transmitted to the Department on a quarterly basis. Requires the Department to create forms to be used for the reports and that the forms shall not request or require identifying information of the patient or the health care provider. Requires the Department to ensure anonymity of all patients and health care professionals. Provides that all reports are exempt from disclosure under the Freedom of Information Act and are confidential and that access to the reports shall be limited to authorized Department staff for statistical purposes only. Makes a conforming change in the Freedom of Information Act.

Creates the Classification by Biological Sex Act. Sets forth findings. Provides that any public school or school district and any State, local agency, department or office that collects vital statistics for the purpose of complying with antidiscrimination laws or for the purpose of gathering accurate public health, crime, economic, or other data shall classify each individual who is part of the collected data set as either male or female at birth. Amends the Statute on Statutes. Sets forth the meaning of the following terms as used in any statute or any rule or regulation: a person's sex; female and male; woman and girl; man and boy; and mother and father.

Amends the School Code. Provides that school districts may regulate and restrict access to public restrooms, locker rooms, dressing rooms, and other similar places on the basis of biological sex and may also adopt a policy that provides for gender neutral or alternative facilities for students, staff, and members of the public, as the school district deems appropriate. Provides that school districts are not required to: (1) adopt a policy that restricts or regulates access to public restrooms, locker rooms, dressing rooms, and other similar places on the basis of biological sex; (2) adopt a policy that includes the facilitation of gender neutral or alternative facilities for students, staff, and members of the public; (3) limit access by a minor accompanied by an adult guardian of the opposite sex into a specified facility appropriate for the adult guardian; (4) prohibit a person with disabilities from using a specified facility appropriate to the biological sex of either the person with disabilities or of an adult caretaker providing assistance; (5) prohibit access to these facilities by custodial staff, school staff, or other persons in an emergency situation; or (6) alter their current policies on access to public restrooms, locker rooms, dressing rooms, and other similar places.